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61% of GLP-1 users reported feeling positive about their body image and confidence while on the medication, up from 46% before starting it
An extension analysis of patients from Novo Nordisks own STEP1 trial found that one year after withdrawal of onceweekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained twothirds of their prior weight loss, with similar changes in cardiometabolic variables. If weight rebound is common after cessation of Wegovy and other GLP-1s, payers who cover these drugs may well need to plan for an enormous per-member expenditure for patients who stay on GLP-1s indefinitely
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