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B12 deficiency elevates homocysteine, a sulfur-containing amino acid that damages arterial endothelium and increases atherosclerosis risk
The medicines being considered for reclassification are typically those that treat common, self-limiting conditions or those where the risk can be managed with pharmacy intervention
Store at between 15 and 30C (59-86F)
These detection times vary with each drug and personal factors, such as individual metabolism
For inflammatory bowel disease, mesalamine, corticosteroids, immunomodulators (azathioprine, methotrexate), and biologics (infliximab, adalimumab, vedolizumab, ustekinumab) all have Level 1 evidence from Phase III trials with thousands of patients
