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A single dominant pathway appears unlikely to account for all cases of melanocyte loss in vitiligo, and apparently, a complex interaction between genetic, environmental, biochemical and immunological events is likely to generate a permissive milieu Human skin is constantly exposed to a broad array of physical, chemical and biological agents, many of which are either inherent oxidants or catalyse the generation of ROS
The robust evidence base described above applies to topical and dietary delivery
doi:10.1002/jor.21107
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