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Indications and Usage Saxenda (liraglutide) injection 3 mg is indicated in combination with reduced-calorie diet and increased physical activity to reduce excess body weight and maintain weight reduction long term in: Adults and pediatric patients aged 12 years and older with body weight greater than 60kg and obesity Adults with overweight in the presence of at least one weight related comorbid condition Limitations of Use Saxenda contains liraglutide and should not be coadministered with other liraglutide-containing products or with any other GLP-1 receptor agonist The safety and effectiveness of Saxenda in pediatric patients with type 2 diabetes have not been established Reference 1
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Subsequently, we applied a focused refinement approach on the particles used in the reconstruction of holo-complex to improve the resolution for c-MET I and HGF I, resulting in a new cryo-EM map with resolution improved to 4.5 , which allowed us to build reliable models for the K3 and K4 domains of HGF (Supplementary Figs
Glucose metabolism and insulin receptor signal transduction in Alzheimer disease
