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TPL has been encapsulated or adsorbed onto the surfaces of nanoparticles, such as liposomes and polymer nanoparticles, which significantly improves its solubility and dispersibility in water

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Common fillers that may cause reactions include: Lactose Cornstarch Polyethylene glycol (PEG) Povidone Carboxymethylcellulose Gelatin Dyes such as brilliant blue, sunset yellow FCF, allura red, indigo carmine Propylene glycol Mannitol Sucrose Compounding pharmacies, like CareFirst Specialty Pharmacy, can customize medications by removing fillers that may trigger mast cell activation

*Vitamin B12* is also essential for DNA synthesis and energy production

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