Other reported mechanisms include activation of FAK-paxillin complexes (which help cells migrate and attach to surfaces during wound healing), JAK-2 signaling, and ERK1/2 pathway activity (Sikiric et al., Current Neuropharmacology, 2016
doi:10.1093/ajcn/80.6.1551 Funk RS, Jones J, Polireddy K, et al
BPC-157 has been shown in research settings to influence angiogenic signaling, nitric oxide pathways, and fibroblast activity, while TB-500 has been studied for its role in actin regulation, cell migration, and wound-healing mechanisms
Another issue is pain
In addition to physiological changes that occur with aging, and also social risk factors, the elderly population is at a risk for protein malnutrition and vitamin deficiency