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A large, multicenter study published in JAMA Ophthalmology and covering 37.1 million adults with type 2 diabetes compared patients initiating semaglutide with those on other antidiabetic medications

Preclinical and clinical studies suggest potential effects on bone metabolism, with evidence that GLP-1 receptor activation may support bone formation and remodeling

Oxidative stresscharacterized by excessive production of reactive oxygen species (ROS)is both a cause and consequence of chronic inflammation, creating a self-perpetuating cycle of tissue damage

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