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Glucagon can boost metabolism and signal the brain to eat less

However, hypoglycemia has been reported in up to 9% of overdose cases, even in the absence of insulin or sulfonylurea co-administration, particularly in non-diabetic or lean individuals

Endogenous Glucagon-Like Peptide 1 Controls Endocrine Pancreatic Secretion and Antro-Pyloro-Duodenal Motility in Humans

doi: 10.1016/j.anaerobe.2013.08.006 341 Garcia-GutierrezEOMahonyAKDos SantosRSMarroquLCotterPD