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Or that it contains the stated dose in every batch
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Transcriptomic profiling of GlpNP-treated lesions revealed upregulation of contractile smooth muscle markers (ACTA2, MYH11) and downregulation of inflammatory genes ( IL1B , MMP9 ), supporting a mechanism of dual-cell reprogramming [197]
First, lack of exposure is possible, as we lacked information on patient compliance with prescribed treatments and potential lack of medication dispensed at hospitals, however as medication compliance is similar across all three groups and we defined exposure as redeemed prescriptions, ensuring that the medication was actively collected by the patient, systematic misclassification is unlikely
