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Ngondi 2005)
In addition to phagocytosis, they can secrete bactericidal granule contents after direct activation by the pathogen, either by cytolysis, exocytosis, or piecemeal degranulation (36)
GHK-Cu's stimulation of VEGF and bFGF production supports both acute angiogenic responses to ischemia and long-term maintenance of adequate vascular density in cardiac tissue
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It is generally well-tolerated, with the following side effects [9][18]: GI symptoms (most common): Nausea, vomiting, diarrhea, and abdominal discomfort, particularly at doses above 1,200 mg/day Sulfurous taste/smell: NAC has a distinct sulfur odor and taste that some find unpleasant Headache: Occasionally reported Anaphylactoid reactions (IV use only): Infusion-related reactions including flushing, itching, bronchospasm, and hypotension occur in approximately 10-20% of patients receiving IV NAC for acetaminophen overdose [18] Upper limit: There is no established UL for NAC
