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The requirements include patients at high metabolic or cardiovascular risk with a BMI greater than 27 with prediabetes or established cardiovascular disease, or a BMI over 30 with uncontrolled hypertension despite treatment, advanced kidney disease, or heart failure
It is not a medical term but describes a recognisable pattern
We propose that comparable approaches aimed at developing agents targeting IGF-1R downstream signaling molecules specifically implicated in each type of cancer on a case-by-case basis could have better anticancer resistance effects with less toxicity
SOD, t -test = 0.39, P = 0.70
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