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Neither peptide is FDA-approved as a standalone therapeutic, and evidence specific to perimenopausal populations remains limited

Light and watery ampoule texture that is quickly absorbed into the skin

The medication is administered via subcutaneous injection, typically on a weekly basis, though dosing frequency and amounts may be individualized based on patient response and tolerability

It does not require a prescription in the traditional sense, but obtaining it through proper channels has become more difficult with the Category 2 classification

injectables may reach higher local concentrations but lack extensive human trial data and FDA approval for this purpose