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GPR120 shows very little sequence similarities to the other free fatty acid receptors but, likewise, is found to be expressed by the enteroendocrine cell system, especially in the colon (see Figure 3), but also in the lungs (267), white and brown adipose tissue (274, 275), hypothalamic microglia (253), macrophages and, contrarily to GPR40, not in -cells but in somatostatin producing -cells (276)

One study conducted in 2014 found that the intake of 2 g of L-arginine per day for 45 days improved the lipid profile and fasting blood sugar levels among male athletes

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