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Additionally, weight reduction associated with GLP-1 therapy often correlates with symptom improvement in IBS patients, as excess weight can exacerbate abdominal discomfort and bowel dysfunction
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As a result, investigators have increasingly explored whether GLP-1 therapy might confer protection against colorectal neoplasia, either as a direct biological effect or as a consequence of improved metabolic health
By means of the enzyme lysine-specific demethylase (LSD-1), it ensures the demethylation of histones, whereby some genes are increasingly expressed
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