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One stimulates the pituitary through GHRH pathways, while the other acts through ghrelin receptors, creating a broader signal for natural growth hormone release
It is not licensed by the MHRA, is not available on NHS prescription, and has not been appraised by NICE for any indication
Same pituitary receptor as sermorelin, same downstream GH release
This is different from exogenous GH or GHRH-style peptides, which raise systemic GH and affect every tissue
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