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One article proposed that excessive serotonin levels could explain classic symptoms of ME/CFS (433), as it would promote the release of excess CRH, and therefore cause chronic reactivation of the HPA axis (434)

Instead, they focus on more-common ingredients, like amino acids, protein, creatine, and caffeine

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Ginsenoside Rh1 bioavailability was 1.01% in one study, highlighting pre-systemic metabolism as a partial explanation [223]

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