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Myoblast Proliferation and Anti-Differentiation Yang and Goldspink (2002) in FEBS Letters the foundational paper for synthetic MGF E-peptide research confirmed that MGF E-domain peptide increases myoblast proliferation while inhibiting terminal differentiation of C2C12 cells, in contrast to mature IGF-1 which primarily promotes differentiation with a lesser proliferative effect
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Wankhade UD, Lee JH, Dagur PK, Yadav H, Shen M, Chen W, Kulkarni AB, McCoy JP, Finkel T, Cypess AM, Rane SG
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