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Once p53 is freed, it moves out of the nucleus toward the mitochondria and sets off the intrinsic apoptosis pathway (a caspase-driven self-destruct program)
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They also serve as powerful antioxidants, neutralizing harmful free radicals and supporting many bodily functions
In 2018 PCOS was recognised as a major public health issue for women ( Polycystic Ovary Syndrome Challenges 2018 )
Mutations in tumor suppressor genes 1 and 2 (BRCA1 and BRCA2), which are involved in repairing damaged DNA, are among the genetic factors studied
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