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Tendon and Ligament Repair Moderate to Strong Evidence Evidence Rating: Moderate-Strong (Several animal studies, some independent replication) Research support for musculoskeletal healing is substantial: Achilles tendon injuries Ligament damage (MCL, ACL) Rotator cuff healing General tendinopathy Surgical repair enhancement The FAK-paxillin mechanism and VEGF upregulation provide clear biological rationale for these effects
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Autotomy behavior correlates with the DRG and spinal expression of sodium channels in inbred mouse strains
TB-500 is systemically acting - distributes throughout the body via actin regulation, dosed in milligrams (25 mg), given twice weekly
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