In addition to slowing gastric emptying to make you feel full for longer, GLP-1 also plays a direct role in how your appetite is regulated which in turn affects how much you eat on a daily basis
As body composition changes and insulin sensitivity improves, patients may experience shifts in various hormones that regulate sleep, including cortisol, growth hormone, and leptin
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in their work with their in vitro BBB models [37]
Biomarker-Guided Dosing: Beyond Weight and HbA1c Fasting insulin, HOMA-IR, and C-peptide levels indicate baseline insulin resistance severity, informing whether a microdose approach will sufficiently activate GLP-1 pathways or if faster titration is warranted