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The existing collagen fibers become disorganized, fragmented, and infiltrated with mucoid, non-structural material (ground substance)
store reconstituted material at 4C and use within ~30 days
ARA-290 (Cibinetide) is a synthetic 11-amino-acid non-hematopoietic erythropoietin-derived peptide
No lethal dose (LD50) has ever been determined because it has proven impossible to kill an animal with DSIP at any dose a remarkable finding for any bioactive compound
doi: 10.1126/science.aad9903 162 TakahashiYTokuokaSMasudaTHiranoYNagaoMTanakaHet al
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