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Research Framework 2.3.1
Compared to L-arginine, an advantage to supplementation with L-citrulline is that intestinal catabolism of L-citrulline is limited since it is not metabolized by arginases, and the activity of arginosuccinate synthase is low in enterocytes [2]
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Reduced kidney function and folate status are major confounders, since both can raise MMA and/or homocysteine independently of B12
If youre worried about your B12 intake, you can come to the clinic and get treatment
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