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Gait speed over 4 meters takes about the same

Some people find theyre reaching their goals and tolerating treatment well at a lower dose, while others may benefit from stepping up

Phase 2 clinical trial data published in 2023 in the New England Journal of Medicine (Jastreboff et al., NEJM 2023) demonstrated substantial weight reduction in participants with obesity

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Myokines produced by skeletal muscle, such as interleukin-6 (IL-6) and irisin, play a key role in mediating these immune and metabolic responses through autocrine, paracrine, and endocrine effects