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Importantly, these medications carry a boxed warning for risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), and are contraindicated in patients with personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2

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Nolfi-Donegan D, Braganza A, Shiva S (2020) Mitochondrial electron transport chain: oxidative phosphorylation, oxidant production, and methods of measurement

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