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While there is no absolute contraindication, alcohol can: Increase nausea and gastrointestinal distress Contribute empty calories that undermine weight management efforts Potentially increase the risk of hypoglycemia in patients also taking diabetes medications Impair judgment regarding portion control and food choices Potentially increase pancreatitis risk, especially with heavy consumption Patients should discuss alcohol use with their healthcare provider and, if consuming alcohol, do so in moderation (defined as up to one drink per day for women and up to two drinks per day for men)
Clinicians should counsel patients about these expected effects and emphasize the importance of gradual dose titration to minimize gastrointestinal intolerance
1 2 3 4 Li Y, Perry T, Kindy MS, Harvey BK, Tweedie D, Holloway HW, Powers K, Shen H, Egan JM, Sambamurti K, Brossi A, Lahiri DK, Mattson MP, Hoffer BJ, Wang Y, Greig NH (January 2009)
And the larger clinical trial evidence (STEP 9 in knee osteoarthritis patients, the SLIM LIVER study) supports the view that the disproportionately larger loss of fat relative to LBM results in improved mobility and physical function, even when absolute LBM declines
It is obvious that healthy lifestyle should be the mainstay of the treatment
