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In contrast, T-helper 1 (T H 1) immunity is highly limited and gradually develops during the postnatal period (142144)
Some patients may also experience mild temporary side effects such as: Injection site soreness Redness or swelling Headache Nausea Mild muscle cramping These effects are generally mild and resolve quickly
Disruption of this regulatory circuit, as observed in PD patients with lower heart rate variability (a sign of vagal dysfunction), causes exacerbated systemic inflammation and greater microglial priming once peripheral cytokines or endotoxins reach the CNS [121]
In earlier clinical trials, IGV-001 demonstrated good tolerance and safety (NCT02507583)
2024XY184, 2023KY550, 2023KY1275 and 2025KY125)
