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For Asn240, the k cat value for tyramine was reduced 457-fold, while the k cat values for the diphenols dopamine and L -DOPA were reduced 37-fold and 103-fold, respectively, in comparison to jr PPO1-wt (Table 2)
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Seizure episodes are defined as "transient symptoms and/or signs due to abnormal and simultaneous neuronal activity of a population of neuronal cells in the brain" [2]
KPV NF-kB suppression would affect inflammation regardless of location
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