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It is ideal for individuals dealing with sun damage or skin discolouration
But once metabolic pressure is relieved, it is often mobilised earlier than subcutaneous fat
At Bay Clinic, Medical Directors Dr Bernard Tan and Dr Hoe Ying Min have 20+ years of combined experience and have treated thousands of patients with successful outcomes
At the systemic level, GLP-1 RAs improve insulin sensitivity in peripheral tissues (muscle, adipose), reduce circulating free fatty acid flux to the liver, suppress hypothalamic appetite circuits to promote weight loss, and lower systemic pro-inflammatory cytokines (TNF-, IL-1, IL-6), thereby reducing the hepatic inflammatory milieu indirectly [7,26,30]
Adequate protein intake is the primary mitigation strategy
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