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More serious but less common adverse effects observed across the incretin drug class and under investigation for retatrutide include: Pancreatitis : Seek urgent medical attention if you experience severe, persistent abdominal pain, particularly if it radiates to the back
4 One study showed these tend to be mild to moderate, occurring primarily when increasing dosage levels
Since muscle supports metabolism, changes in testosterone and lean muscle mass may make weight loss slower
The side effects are worse just after starting treatment and in the days after increasing the dose
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