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In laboratory and pre-clinical research settings, 5-Amino-1MQ is used as a molecular probe to investigate the consequences of NNMT inhibition across multiple metabolic and cellular systems
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Cancer: Many forms of cancer stem from alcohol abuse, such as cancers of the head and neck, esophagus, liver, breast and colon
To evaluate the role of TGF signalling in high glucose-induced PSC activation, we treated cells in the low-glucose group with 5 ng/mL TGF1 and cells in the high-glucose group with 10 M of the TGF pathway inhibitor SB431542
E.et al (2008)
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