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They can also increase due to environmental factors such as pollution, smoking, poor diet, chronic stress, and excessive alcohol consumption
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Generation of ROS by the labile iron pool Per its name, ferroptosis requires iron, which can catalyze lipid peroxidation
This is supported by the finding that aging leads to more oxidation of the GSH and more damaged mtDNA in the mitochondria, which can be prevented by oral antioxidant administration
Figure 1 Oxidative stress and antioxidants in SARS-CoV-2 Small increase in ROS cellular levels act as signaling molecules in the preservation of cells physiological functions a process known as redox biology
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