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Back GBD 2019 Risk Factor Collaborators (2020) 'Global Burden of 87 Risk Factors in 204 Countries and Territories, 19902019: a systematic analysis for the global burden of disease study 2019', The Lancet , 396, 122349
There were ~2,500 in 2022, 4,700 in 2023, 8,500 in 2024 and 10,745 through September 2025
Traditional subcutaneous injection provides the highest bioavailability, typically 80-95% of the administered dose reaching systemic circulation
does not constitute medical advice or imply efficacy in humans
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