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This mechanism extends beyond simple angiogenesis to sophisticated vascular reprogramming

Insulin resistance may occur in some patients with diabetes, requiring higher insulin doses for adequate glycemic control

Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Insulin Glargine as Add-on to Metformin (With or Without Sulfonylureas) in Insulin-Naive Patients With Type 2 Diabetes (SUSTAIN 4): A Randomised, Open-Label, Parallel-Group, Multicentre, Multinational, Phase 3a Trial

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DOI: 10.2174/1872213X13666191026090713