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The trial participants were at very high risk for subsequent cardiovascular events with 68% having had a heart attack (82% had coronary artery disease) and the rest with prior stroke or peripheral arterial disease or a combination of these entry criteria
The combination of MOTS-C and Retatrutide targets what many researchers consider the two biggest weaknesses of aggressive weight loss protocols: energy crashes and muscle loss
doi: 10.3389/fpsyt.2025.1555370 Received 06 January 2025 Accepted 25 July 2025 Published 19 August 2025 Volume 16 - 2025 Edited by Veena Kumari, Brunel University London, United Kingdom Reviewed by Krupa Vakani, Imperial College, United Kingdom Updates Copyright 2025 Shen, Zhao, Pei, Wang, Hou, Chai, Guo, Li, Hao and Wu
Chem Rev
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