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SGLT2 inhibitors, such as canagliflozin empagliflozin and dapagliflozin, suppress TEC apoptosis to ameliorate diabetic kidney damage (119, 124, 125)

Histamine-rich foods: Foods like aged cheeses, fermented products, and cured meats can exacerbate histamine intolerance due to their high histamine content

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Transcription factors such as sterol regulatory element-binding proteins (SREBPs) and liver X receptors (LXRs) regulate the expression of key enzymes involved in PC synthesis in response to cellular lipid and metabolic status

Dose and format determined at intake