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J Am Coll Nutr 1993;12:147-54
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These agents are FDA-approved primarily for the management of type 2 diabetes mellitus and, for specific products (Wegovy, Saxenda, Zepbound), for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity
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Overall, GPX4 inhibitors could have a combined effect on eliminating senescent cells in the tumour and tumour microenvironment and the subset of highly plastic, mesenchymal-like cells that promote therapy resistance
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