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Initial treatment often involves 1000 mcg intramuscular injections daily for 7 days, then weekly for a month

The choice between Vitamin B12 supplements vs injections depends on several factors, including: Your needs: If you have a severe B12 deficiency or require rapid B12 replenishment, B12 shots may be the more effective option

You may need B12 injections if you: Have been diagnosed with pernicious anemia Have gastrointestinal issues (e.g., Crohns disease, celiac disease, or after bariatric surgery) Follow a strict vegan or vegetarian diet without adequate supplementation Are over the age of 50, as absorption decreases with age Take certain medications that interfere with B12 absorption Have chronic fatigue, memory issues, or nerve problems due to B12 deficiency

Many patients also transition to alternating B12 one month and Skinny Shot the next for broad coverage