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It works by inhibiting the NNMT enzyme, which is associated with fat storage, insulin resistance, and reduced cellular energy
At an average elimination rate of .015, it would take him roughly 4 hours just to be at .08
For patients who experience a paradoxical decrease in energy levels, it doesnt mean you should stop taking the B12 but instead decrease your dose by half (so take 2,500mcg every 7 days) or simply take 5,000mcg every 14 days instead
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