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Moreover, it does not appear to impact hunger hormone signaling to either increase or decrease appetite
However, observational studies suggest that whilst acute toxicity remains exceptionally rare, sustained very high levels of B12particularly from supplements or injectionsmay be associated with certain health concerns, though these are correlations rather than proven causal relationships
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Safety Research Priorities Comprehensive long-term safety studies are critically needed, particularly given concerns about potential effects on cancer development and progression
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