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These findings held true for both men and women, regardless of age

They are potent stimulators of postprandial insulin secretion under hyperglycemic conditions and contribute to approximately 70% of the physiological postprandial insulin secretion

Contraindications to semaglutide include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, and previous serious hypersensitivity to semaglutide or any formulation components