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This aggressive PDA is caused by inducing epithelial-mesenchymal transition (EMT) and upregulating matrix metalloprotease-2 (MMP-2) expression to enhance the motility of PDAC cells (Zelenko et al., 2016

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[14] Tirzepatide, as a dual GIP/GLP-1 receptor agonist, may achieve higher weight reductions (15-22%) but is currently licensed only for diabetes in the UK

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