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Elevated plasma glucose-dependent insulinotropic polypeptide associates with hyperinsulinemia in impaired glucose tolerance
Medications are considered secondary tools, used only when patients meet specific health criteria
However, skeletal muscle-specific carnitine palmitoyltransferase 2 (CPT2)-deficient mice accumulate large amounts of acylcarnitine in muscle and plasma and still preserve insulin sensitivity [75], highlighting the role of acylcarnitine only as an indicator of FAO rather than as a direct mediator of insulin resistance [76]
Lipid accumulation in L02 cells after FFA treatment could cause increased ROS, mitochondrial damage, and ferroptosis
2003 Nov;8(4):359-77
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