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Designing probes that can produce different reaction products or bind specifically to GSH rather than Cys and Hcy can help improve specificity
ClinicalTrials.gov identifier: NCT06309667
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This discovery ultimately led Howard and colleagues to clone the GH secretagogue receptor in 1996, and Kojima and colleagues to identify ghrelin as its endogenous ligand in 1999 establishing the entire ghrelin system in biology
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