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Cortical bone demonstrated elevated porosity and reduced tibial cortical thickness, resulting in declines of 5.7%, 5.5%, and 5.2% in tibial compressive strength, stiffness, and apparent modulus, respectively

11 , eadr1728 (2025)

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In animal studies, this build-up has been associated with decreased semen quality, most likely due to inflammation and oxidative stress-induced damage