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The pivotal trial supporting its 2010 FDA approval enrolled 816 HIV-infected adults with clinically defined lipodystrophy, and Phase 3 data documented visceral fat reductions of roughly 15-18% over 26 weeks of treatment a result robust enough to clear FDA review for a defined medical indication
You've probably heard that free radicals are a big part of the human aging process
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Slower digestion means more time for gut bacteria to ferment food, which can produce gas, and more time for the colon to reabsorb water, which can make stool harder to pass
Moreover, in diabetes, mechanisms that normally counteract increased oxidative stress, such as upregulation of HO-1, are impaired, leading to loss of ICC and subsequent delay in gastric emptying
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