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Maculopapular eruptions on back (a) and left forearm (b) 27 days after onset of the rash
Specifically, it is manifested as a decrease in the mitochondrial DNA content, a reduction in the activity of electron transport chain complexes (such as complexes I and II), and a weakened ability to generate ATP, a key product of cellular energy metabolism [30]
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Asparagine deprivation promotes ROS-dependent ATF4 expression in CD8 + T cells, leading to their functional improvement and antitumor immune responses in a mouse melanoma model [220, 221]
Typical starting values for orientation
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