Studies directly characterizing the effects of treatment with tirzepatide in patients with T2D and/or obesity and COVID-19 or long COVID have not been published yet
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Moreover, the activity of p53 can be regulated by various PTMs, including lactylation, acetylation, succinylation, UFMylation, and -hydroxybutyrylation
Importantly, our cell culture observations were corroborated by our results obtained in animal studies, suggesting that increased hepatic protein S -glutathionylation contributes to NAFLD pathogenesis via suppression of the NF-B signaling pathway in hepatocytes
Cardiovasc Res (2020) 116(5):91630