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3.4 Transcription factors and ferroptosis P53 and Nrf2, as widely reported transcription factors, participate in the metabolism of iron and reactive oxygen species by regulating SLC7A11, arachidonate 12-lipoxygenase (ALOX12) gene, NOQ1, HO-1, heme type I fluorosynthase and the frontotemporal hairline (FTHL) gene (33)
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Furthermore, emerging tools such as in silico methodologies (105), and the Nutraceutical Interaction Risk Score (NIRS) (106), offer valuable resources for clinicians
This product is best understood as a copper-peptide research material for matrix and cell-signalling studies
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