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Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena

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Research published in BioScientifica confirms that GLP-1 receptors are located directly in the Ventral Tegmental Area (VTA) and the Nucleus Accumbens the parts of the brain that control wanting and craving. By dampening the dopamine hit we get from a binge, these medications can effectively decondition the brains reliance on food for pleasure

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