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By omitting two daily doses (48 h), we would have covered the stipulated five half-lives for the drug to be cleared from the system so as not to influence the GLP-1 secretion

Umashankar N, Agarwal KC, Purohit G, et al

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The uptake on ascorbate from the lumen of the small intestine as well as its transport into cells is the function of two Na + -dependent vitamin C co-transporters identified as SVCT1 and SVCT2